X-LRT is a suite of family-based tests for detecting association of X-chromosome
genes. This is a likelihood-based approach which can perform hypothesis testing
as well as estimation of disease-related marker relative risks under a case-parent
design. This test uses nuclear family with a single affected proband and allows
additional siblings and missing parental genotypes. This program can test both
single marker and haplotypes association. The detail of the theoretical works
can be found at Zhang et al. (2008)
Zhang L, Martin ER, Chung RH, Li YJ, Morris RW. (2008) X-LRT: a likelihood approach
to estimate genetic risks and test association with X-linked markers using a
case-parents design. Genetic Epidemiology May;32(4):370-80.
X-LRT, version 1.0, is compiled for the Windows platform.
Please fill out the form below to download. Enter the following
in the "Input Word" field: XLRT_SOFTWARE